Congratulations to Dr. Debbie Stephens who just published a first author article in Blood (133, 1298-1307, 2019) entitled, “How I manage ibrutinib intolerance and complications in patients with chronic lymphocytic leukemia.” Ibrutinib is widely used as a therapeutic for CLL, but adverse side effects of the treatment are often encountered. In this article Dr. Stephens discusses management of patients on ibrutinib.