Top Research Publications: June 2021
Note: Names in bold are faculty members in the Department of Internal Medicine.
Cardiovascular Medicine
Wohlfahrt P, Nativi-Nicolau J, Zhang M, Selzman CH, Greene T, Conte J, Biber JE, Hess R, Mondesir FL, Wever-Pinzon O, Drakos SG, Gilbert EM, Kemeyou L, LaSalle B, Steinberg BA, Shah RU, Fang JC, Spertus JA, Stehlik J. Quality of Life in Patients With Heart Failure With Recovered Ejection Fraction JAMA Cardiol. 2021. DOI: 10.1001/jamacardio.2021.0939. PMID: 33950162.
Marashly Q, Taleb I, Kyriakopoulos CP, Dranow E, Jones TL, Tandar A, Overton SD, Tonna JE, Stoddard K, Wever-Pinzon O, Kemeyou L, Koliopoulou AG, Shah KS, Nourian K, Richins TJ, Burnham TS, Welt FG, McKellar SH, Nativi-Nicolau J, Drakos SG. Predicting mortality in cardiogenic shock secondary to ACS requiring short-term mechanical circulatory support: The ACS-MCS score Catheter Cardiovasc Interv. 2021 Mar 7. DOI: 10.1002/ccd.29581. PMID: 33682308.
Bieging ET, Morris A, Chang L, Dagher L, Marrouche N, Cates J. Statistical shape analysis of the left atrial appendage predicts stroke in atrial fibrillation. Int J Cardiovasc Imaging. 2021 May 6. https://doi.org/10.1007/s10554-021-02262-8.
Endocrinology, Metabolism & Diabetes
Farhat R, de Santana-Van Vliet E, Su G, Neely L, Benally T and Chan O. Carvedilol Prevents Impairment of the Counterregulatory Response in Recurrently Hypoglycemic Diabetic Rats. Endocrinol, Diabetes and Metab. 2021 (In Press) DOI: 10.1002/EDM2.226. Epub 2021 Feb 6.
Moriwaki M, Welt CK PRL Mutation Causing Alactogenesis: Insights into Prolactin Structure and Function Relationships J Clin Endocrinol Metab. 2021 Mar 26:dgab201. doi: 10.1210/clinem/dgab201. Online ahead of print. PMID: 33770166.
Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon RG, Nair VD, Seenarine N, Amper MAS, Zhou X, Ongaro L, Toufaily C, Schang G, Nery JR, Bartlett A, Aldridge A, Jain N, Childs GV, Troyanskaya OG, Ecker JR, Turgeon JL, Welt CK, Bernard DJ, Sealfon SC. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 May 11;12(1):2677. doi: 10.1038/s41467-021-22859-w.PMID: 33976139.
Epidemiology
Bress AP, Cohen JB, Anstey DE, Conroy MB, Ferdinand KC, Fontil V, Margolis KL, Muntner P, Millar MM, Okuyemi KS, Rakotz MK, Reynolds K, Safford MM, Shimbo D, Stuligross J, Green BB, Mohanty AF. Inequities in Hypertension Control in the United States Exposed and Exacerbated by COVID-19 and the Role of Home Blood Pressure and Virtual Health Care During and After the COVID-19 Pandemic. J Am Heart Assoc. 2021 May 19:e020997. doi: 10.1161/JAHA.121.020997. Online ahead of print. PMID: 34006116.
Pugh MJ, Kennedy E, Prager EM, Humpherys J, Dams-O'Connor K, Hack D, McCafferty MK, Wolfe J, Yaffe KC, McCrea M, Ferguson AR, Lancashire L, Ghajar J, Lumba-Brown A. Phenotyping the Spectrum of Traumatic Brain Injury: A Review and Pathway to Standardization. J Neurotrauma. 2021 Apr 15. doi: 10.1089/neu.2021.0059.
Richard E. Nelson, Ann Elizabeth Montgomery, Ying Suo, James Cook, Warren Pettey, Adi Gundlapalli, Tom Greene, William Evans, Lillian Gelberg, Stefan Kertesz, Jack Tsai, Thomas Byrne. Temporary financial assistance leads to decreases in healthcare costs for Veterans experiencing housing instability. Health Aff (Millwood). 2021 May;40(5):820-828. doi: 10.1377/hlthaff.2020.01796.PMID: 33939508.
Gastroenterology, Hepatology & Nutrition
Qayed E, Sheth SG, Aihara H, Anand GS, Byrne KR, Chahal P, Dacha S, James T, Kowalski TE, Repaka A, Saadi M, Taylor JR, Williams RL, Wagh MS; (ASGE Training Committee Chair). Advanced endoscopy fellowship training in the United States: recent trends in American Society for Gastrointestinal Endoscopy advanced endoscopy fellowship match, trainee experience, and postfellowship employment. Gastrointest Endosc. 2021 Apr 5:S0016-5107(21)00088-2. doi: 10.1016/j.gie.2021.01.027. PMID: 33832739.
Gawron AJ, Horner B, Zurbuchen R, Boynton K, Fang J. A comprehensive intervention to enhance inpatient colon preparation quality for colonoscopy. Minerva Gastroenterol (Torino). 2021 Apr 1. doi: 10.23736/S2724-5985.21.02766-5. Online ahead of print. PMID: 33793164.
Walsh CM, Qayed E, Aihara H, Anand GS, Byrne K, Chahal P, Dacha S, James TW, Kowalski TE, Repaka A, Saadi M, Sheth SG, Taylor JR, Williams RL, Wagh MS. Core curriculum for ergonomics in endoscopy. Gastrointest Endosc. 2021 Apr 2:S0016-5107(21)00050-X. doi: 10.1016/j.gie.2021.01.023. Online ahead of print. PMID: 33820648.
General Internal Medicine
Stagg BC, Gupta D, Ehrlich JR, Newman-Casey PA, Stein JD, Kawamoto K, Hess R. Evaluation for Disparities in Experience With Internet-Based Health Care Among US Patients With Chronic Eye Diseases. JAMA Ophthalmol. 2020 Oct 1;138(10):1097-1099. doi: 10.1001/jamaophthalmol.2020.3016. PMID: 32852514; PMCID: PMC7453339.
Jones WS, Mulder H, Wruck LM, Pencina MJ, Kripalani S, Muñoz D, Crenshaw DL, Effron MB, Re RN, Gupta K, Anderson RD, Pepine CJ, Handberg EM, Manning BR, Jain SK, Girotra S, Riley D, DeWalt DA, Whittle J, Goldberg YH, Roger VL, Hess R, Benziger CP, Farrehi P, Zhou L, Ford DE, Haynes K, VanWormer JJ, Knowlton KU, Kraschnewski JL, Polonsky TS, Fintel DJ, Ahmad FS, McClay JC, Campbell JR, Bell DS, Fonarow GC, Bradley SM, Paranjape A, Roe MT, Robertson HR, Curtis LH, Sharlow AG, Berdan LG, Hammill BG, Harris DF, Qualls LG, Marquis-Gravel G, Modrow MF, Marcus GM, Carton TW, Nauman E, Waitman LR, Kho AN, Shenkman EA, McTigue KM, Kaushal R, Masoudi FA, Antman EM, Davidson DR, Edgley K, Merritt JG, Brown LS, Zemon DN, McCormick TE 3rd, Alikhaani JD, Gregoire KC, Rothman RL, Harrington RA, Hernandez AF; ADAPTABLE Team. Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease. N Engl J Med. 2021 May 27;384(21):1981-1990. doi: 10.1056/NEJMoa2102137. Epub 2021 May 15. PMID: 33999548.
Wegrzyn G, Walborn A, Rondina M, Fareed J, Hoppensteadt D. Biomarkers of Platelet Activation and Their Prognostic Value in Patients With Sepsis-Associated Disseminated Intravascular Coagulopathy. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029620943300. doi: 10.1177/1076029620943300. PMID: 33586482; PMCID: PMC7894689.
Geriatrics
Trott DW, Islam MT, Buckley DJ, Donato AJ, Dutson T, Sorensen ES, Cai J, Gogulamudi VR, Phuong TT, Lesniewski LA. T lymphocyte depletion ameliorates age-related metabolic impairments in mice. GeroScience. 2021 Apr 24. Online ahead of print. Doi.org/10.1007/s11357-021-00368-4. PMID: 33893902
Hematology & Hematologic Malignancies
Chien HC, Morreall D, Patil V, Rasmussen KM, Yong C, Li C, Passey DG, Burningham Z, Sauer BC, Halwani AS. Treatment Patterns and Outcomes in a Nationwide Cohort of Older and Younger Veterans with Waldenström Macroglobulinemia, 2006-2019. Cancers (Basel). 2021 Apr 4;13(7):1708. doi: 10.3390/cancers13071708. PMID: 33916545; PMCID: PMC8038459.
Selzman CH, Tonna JE, Pierce J, Vargas C, Skidmore C, Lewis G, Hatton ND, Phillips JD. A pilot trial of human amniotic fluid for the treatment of COVID-19. BMC Res Notes. 2021 Jan 22;14(1):32. doi: 10.1186/s13104-021-05443-9. PMID: 33482902; PMCID: PMC7820830.
Kelley KC, Grossman KF, Brittain-Blankenship M, Thorne KM, Akerley WL, Terrazas MC, Kosak KM, Boucher KM, Buys SS, McGregor KA, Werner TL, Agarwal N, Weis JR, Sharma S, Ward JH, Kennedy TP, Sborov DW, Shami PJ. A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker. BMC Cancer. 2021 May 7;21(1):510. doi: 10.1186/s12885-021-08242-4. PMID: 33957901; PMCID: PMC8103752.
Infectious Diseases
Chen X, Chen Z, Azman AS, Deng X, Sun R, Zhao Z, Zheng N, Chen X, Lu W, Zhuang T, Yang J, Viboud C, Ajelli M, Leung DT, Yu H. Serological evidence of human infection with SARS-CoV-2: a systematic review and meta-analysis. Lancet Glob Health. 2021. May 9(5), e598-e609. PMID: 33705690.
Reimer JR, Ahmed SM, Brintz B, Shah RU, Keegan LT, Ferrari MJ, Leung DT. Using a clinical prediction rule to prioritize diagnostic testing leads to reduced transmission and hospital burden: A modeling example of early SARS-CoV-2. Clin Infect Dis. 2021 Feb 23:ciab177. doi: 10.1093/cid/ciab177. Online ahead of print. PMID: 33621329 Free PMC article. PMID: 33621329.
Verma D, Mel Church T, Swaminathan S. Epstein-Barr virus lytic replication induces ACE2 expression and enhances SARS CoV-2 pseudotyped virus entry in epithelial cells. J Virol. 2021 Apr 14:JVI.00192-21. doi: 10.1128/JVI.00192-21. Epub ahead of print. PMID: 33853968.
Nephrology & Hypertension
Molnar MZ, Azhar A, Tsujita M, Talwar M, Balaraman V, Bhalla A, Podila PSB, Kothadia J, Agbim UA, Maliakkal B, Satapathy SK, Kovesdy CP, Nair S, Eason JD. Transplantation of Kidneys From Hepatitis C Virus-Infected Donors to Hepatitis C Virus-Negative Recipients: One-Year Kidney Allograft Outcomes. Am J Kidney Dis. 2021 May;77(5):739-747.e1. Doi: 10.1053/j.ajkd.2020.10.017. Epub 2020 Dec 14. PMID: 33333148.
Cho ME, Hansen JL, Sauer BC, Cheung AK, Agarwal A, Greene T. Heart Failure Hospitalization Risk associated with Iron Status in Veterans with CKD. Clin J Am Soc Nephrol. 2021 Mar 29;. Doi: 10.2215/CJN.15360920. [Epub ahead of print]. PMID: 33782035.
Ramkumar N, Stuart D, Peterson CS, Hu C, Wheatley W, Cho JM, Symons JD, Kohan DE. Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury. Circ Res. 2021 Apr 23. doi: 10.1161/CIRCRESAHA.120.317532. Epub ahead of print. PMID: 33890822.
Oncology
Mooney K, Titchener K, Haaland B, Coombs LA, O'Neil B, Nelson R, McPherson JP, Kirchhoff AC, Beck AC, Ward JH. Evaluation of Oncology Hospital at Home: Unplanned Health Care Utilization and Costs in the Huntsman at Home Real-World Trial. J Clin Oncol. 2021 May 17:JCO2003609. doi: 10.1200/JCO.20.03609. PMID: 33999660.
Tagawa ST, Balar AV, Petrylak DP, Kalebasty AR, Loriot Y, Fléchon A, Jain RK, Agarwal N, Bupathi M, Barthelemy P, Beuzeboc P, Palmbos P, Kyriakopoulos CE, Pouessel D, Sternberg CN, Hong Q, Goswami T, Itri LM, Grivas P. TROPHY-U-01: A Phase II Open-Label Study of Sacituzumab Govitecan in Patients With Metastatic Urothelial Carcinoma Progressing After Platinum-Based Chemotherapy and Checkpoint Inhibitors. J Clin Oncol. 2021 Apr 30:JCO2003489. doi: 10.1200/JCO.20.03489. PMID: 33929895.
Chi KN, Chowdhury S, Bjartell A, Chung BH, Pereira de Santana Gomes AJ, Given R, Juárez A, Merseburger AS, Özgüroğlu M, Uemura H, Ye D, Brookman-May S, Mundle SD, McCarthy SA, Larsen JS, Sun W, Bevans KB, Zhang K, Bandyopadhyay N, Agarwal N. Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study. J Clin Oncol. 2021 Apr 29:JCO2003488. doi: 10.1200/JCO.20.03488. PMID: 33914595.
Rheumatology
Van Tiem JM, Steffen M.J., Seaman AT, Miller KL, Wardyn SE, Richards CC, Solimeo SL. Attitudes toward bone health among rural‐dwelling veterans identified as at risk of fracture: a qualitative analysis. JBMR Plus. 2021. May 2; e10501.
Wan MT, Walsh JA, Craig ET, Husni ME, Scher JU, Reddy SM, Leung YY, Ogdie A. A comparison of physical function instruments in psoriatic arthritis: HAQ-DI vs MDHAQ vs PROMIS10 global physical health. Rheumatology (Oxford). 2021 May 14;60(5):2307-2316. Doi: 10.1093/rheumatology/keaa591. PMID: 33313838.